The Chronobiological Hypothesis and Psychosocial Cultural & Genomic Therapies: the example of Parkinson’s Disease and Neurodegenerative Disease

Recent research on Parkinson’s Disease (PD) revealed some common etiopathogenic mechanisms underlying a large range of chronic diseases, and more specifically the deregulation
of chronobiological rhythms that may start in the very beginning of such pathological development. Contrary to the bottom-up tradition, the post- genomic biology provides now a much favorable zeitgeist to integrate holistic interventions in both biomedical research and mainstream medical practice. Such integrative efforts may not only improve our understanding of system-level dynamics about health and disease, but also opens larger possibilities for new clinical options that bring positive pathological evolutions while globally increasing quality of life of patients, caregivers, and their families. To facilitate the transition, we renew the invitation to join our international open source research project in widely testing the Creative Psychosocial Genomic Healing Experience (CPGHE), an evidence-based construction of a holistic and naturalist intervention with its standardized version specially designed to offer easy adaption for scientific investigation towards an evidence-based integration of holistic intervention possibilities.
Key words: Parkinson’s disease, neurodegenerative process, chronic conditions, holistic, chronobiology, integrative medicine.