Impaired intracortical transmission in G2019S leucine rich-repeat kinase Parkinson patients
Academic Article
Publication Date:
2017
abstract:
A mutation in leucine-rich repeat kinase 2 is the most common cause of hereditary Parkinson's disease (PD), yet the neural mechanisms and the circuitry potentially involved are poorly understood.
Iris type:
1.1 Articolo in rivista
Keywords:
LRRK2; Parkinson disease; TMS; cortical plasticity; levodopa; Aged; Antiparkinson Agents; Case-Control Studies; Cerebral Cortex; Female; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Long-Term Potentiation; Male; Middle Aged; Motor Cortex; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Parkinson Disease; Synaptic Transmission; Transcranial Magnetic Stimulation; gamma-Aminobutyric Acid
List of contributors:
Ponzo, Viviana; Di Lorenzo, Francesco; Brusa, Livia; Schirinzi, Tommaso; Battistini, Stefania; Ricci, Claudia; Sambucci, Manolo; Caltagirone, Carlo; Koch, Giacomo
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